{"id":22405,"date":"2016-11-30T22:16:03","date_gmt":"2016-11-30T22:16:03","guid":{"rendered":"http:\/\/nsbri.org\/?p=22405"},"modified":"2016-11-30T22:16:03","modified_gmt":"2016-11-30T22:16:03","slug":"significant-advancement-supportive-care-cancer-patients-published-nature-scientific-reports","status":"publish","type":"post","link":"http:\/\/nsbri.org\/2016\/11\/significant-advancement-supportive-care-cancer-patients-published-nature-scientific-reports\/","title":{"rendered":"Significant advancement in Supportive Care for Cancer Patients published in Nature Scientific Reports"},"content":{"rendered":"

NORWOOD, Mass.<\/span>, Nov. 29, 2016<\/span> \/PRNewswire\/ —\u00a0Entrinsic Health Solutions, Inc., an innovative health sciences company today announced the publication of results from research at the University of Florida<\/span> using enterade\u00ae<\/sup>Advanced Oncology (AO) formulation titled, “An amino acid-based oral rehydration solution (AA-ORS) enhanced intestinal epithelial proliferation in mice exposed to radiation.” The full article can be found in the 23 November, 2016<\/span> issue of Nature Scientific Reports<\/i> at www.nature.com\/articles\/srep37220<\/a>.\u00a0 The article is also available in the News & Media section of the Entrinsic Health Solutions website at www.entrinsichealth.com<\/a>.<\/p>\n

Through backing from the National Space Biomedical Research Institute (NSBRI), a NASA-funded consortium, the study in mice investigated the mechanism responsible for better absorption of electrolytes and nutrients with enterade\u00ae<\/sup> AO<\/i> following radiation exposure. It was hypothesized that increased villus height induced by enterade<\/i> is involved in increased electrolyte and nutrient absorption following irradiation. To study how enterade<\/i> increases the absorptive surface area by increasing villus height, researchers at the University of Florida<\/span>, Department of Radiation Oncology, investigated increased proliferation and the related mechanism both in the presence and absence of enterade\u00ae<\/sup> AO<\/i> following radiation exposure. The study found that enterade\u00ae<\/sup> AO<\/i> increased Lgr5+<\/sup> stem cells; increased proliferation markers, such as p-Erk; and decreased apoptosis markers, such as cleaved caspase-3. This study shows that in situ stem cells and the intestinal epithelial cell proliferation induced by the amino acid combination in enterade\u00ae<\/sup> AO<\/i> increased electrolyte and nutrient absorption by increasing villus height that comprised of mature, differentiated epithelial cells with increased functional capability to absorb electrolytes and nutrients.<\/p>\n

Detailed results of the study showed that enterade\u00ae<\/sup> AO<\/i>:<\/p>\n