SMARTCAP Funded Project From ACell, Inc. Granted Patent

NSBRI congratulates SMARTCAP 2012 awardee ACell, Inc., on the issuance of United States Patent 8802436 titled Methods of manufacturing bioactive gels from extracellular matrix material on August 12, 2014.  The work which led to the patent was funded in part by the SMARTCAP grant and focused on evolving ACell’s marketed wound dressings (MatriStem®) into a gel-based formulation that is more appropriate for use in the space environment. The SMARTCAP grant also supported evaluation of the novel bioactive gel in a wound healing model system. In addition to yielding a form factor more suitable for space, SMARTCAP funding has opened new market opportunities for ACell on Earth as the gel will enable doctors to address a number of difficult-to-treat wounds.

About ACell, Inc.

ACell, Inc. is a leading company in the field of regenerative medicine, focused on the development, manufacturing and commercialization of tissue repair products. Its medical devices are cleared for a variety of indications and are marketed under the brand name “MatriStem.” A privately held company, ACell produces MatriStem at its full scale manufacturing facility in Lafayette, IN, and markets its products to physicians in the U.S. through a national direct sales force. For more information, call (800) 826-2926 or visit

About MatriStem®

MatriStem products are porcine-derived extracellular matrix (ECM) scaffolds that contain the epithelial basement membrane from porcine urinary bladder tissue, or urinary bladder matrix (UBM). UBM is a layer of tissue that facilitates a constructive tissue remodeling response by the patient’s body. It provides MatriStem products with several distinguishable characteristics, including the ability to be resorbed by the patient as it is replaced by site appropriate tissue following implantation; the ability to be used “off-the-shelf” and stored at room temperature, with up to a two year shelf life; and superior ease-of-use characteristics. MatriStem products are indicated for use in a wide range of tissue repair applications and come in a range of sizes and thicknesses. They have been cleared for use in general surgery, gynecological surgery and a wide range of wounds, including diabetic foot ulcers (DFU), venous leg ulcers (VLU), pressure, surgical, and tunneled wounds. Refer to the IFU supplied with each device for indications, contraindications and precautions. All MatriStem devices are made in the USA.